Research Interests

  • Large-scale multivariate statistical learning
  • Statistical machine learning
  • Statistical computing and optimization
  • Population health and healthcare analytics
  • Ecological and environmental statistics


  • Elucidating the impact of nano-agrichemicals on paddy soil health and rice production through combined greenhouse studies and machine learning. USDA (2023-67021-39755). Co-PI (with Dr. Samuel Ma at TAMU); 04/01/2023–03/31/2027.
  • Improving identification of pediatric patients at risk of child physical abuse. The Patterson Foundation. PI on sub-award (with Dr. Amy A. Hunter); 01/31/2023 – 01/30/2025.
  • Integrative learning of fluorescence fluctuations in perovskite quantum dots using a data science assisted single-particle approach. National Science Foundation (CHE-2203854). Co-PI (with Dr. Jing Zhao); 09/01/2022–08/31/2025.
  • Developing suicide risk algorithms for diverse clinical settings using data fusion. National Institutes of Health (R01-MH124740). MPI (with Dr. Robert Aseltine and Dr. Fei Wang); 09/16/2020–06/30/2024.
  • Improving suicide prediction using NLP-derived social determinants of health. National Institutes of Health (R01-MH125027). PI on sub-award (PI: Dr. Hong Yu); 09/01/2020–06/30/2024.
  • Improving the identification and management of suicide risk among patients using prescription opioids (HEAL Supplement). National Institutes of Health (R01-MH112148-03S1). PI on sub-award (PI: Dr. Robert Aseltine); 09/18/2020–06/30/2021.
  • Reciprocal modulation of the microbiome and cellular senescence in metabolic dysfunction. National Institutes of Health (R01-AG068860). PI on sub-award (PI: Dr. Yanjiao Zhou); 09/10/2020–05/31/2025.
  • Comprehensive heterogeneous response regression from complex data. National Science Foundation (IIS-1718798). PI; 09/01/2017– 08/31/2020.
  • Improving the identification of patients at risk of suicide. National Institutes of Health (R01-MH112148). PI on sub-award (PI: Dr. Robert Aseltine);  07/01/2017–06/30/2020.
  • Integrative multivariate analysis with multi-view data. National Science Foundation (DMS-1613295). PI; 09/01/2016–08/31/2019.
  • An integrative statistics-guided image-based multi-scale lung model. U.S. National Institutes of Health (U01-HL114494). PI on sub-award (PI: Dr. Ching-Long Lin); 08/01/2013– 05/31/2018.


Selected Publications

  Methodology & Theory

  Application & Case Study