Research

Research Interests

  • Large-scale multivariate statistical learning; integrative statistical learning
  • Dimension reduction and variable selection
  • Statistical machine learning
  • Statistical computing and optimization
  • Population health and healthcare analytics
  • Ecological and environmental statistics

Grants

  • Developing suicide risk algorithms for diverse clinical settings using data fusion. National Institutes of Health (R01-MH124740). Principal Investigator (with Dr. Robert Aseltine and Dr. Fei Wang); 09/16/2020–06/30/2024.
  • Improving suicide prediction using NLP-derived social determinants of health. National Institutes of Health (R01-MH125027). Principal Investigator on sub-award (PI: Dr. Hong Yu); 09/01/2020–06/30/2024.
  • Improving the identification and management of suicide risk among patients using prescription opioids (HEAL Supplement). National Institutes of Health (R01-MH112148-03S1). Principal Investigator on sub-award (PI: Dr. Robert Aseltine); 09/18/2020–06/30/2021.
  • Reciprocal modulation of the microbiome and cellular senescence in metabolic dysfunction. National Institutes of Health (R01-AG068860). Principal Investigator on sub-award (PI: Dr. Yanjiao Zhou); 09/10/2020–05/31/2025.
  • Comprehensive heterogeneous response regression from complex data. National Science Foundation (IIS-1718798). Principal Investigator; 09/01/2017– 08/31/2020.
  • Improving the identification of patients at risk of suicide. National Institutes of Health (R01-MH112148). Principal Investigator on sub-award (PI: Dr. Robert Aseltine);  07/01/2017–06/30/2020.
  • Integrative multivariate analysis with multi-view data. National Science Foundation (DMS-1613295). Principal Investigator; 09/01/2016–08/31/2019.
  • An integrative statistics-guided image-based multi-scale lung model. U.S. National Institutes of Health (U01-HL114494). Principal Investigator on sub-award (PI: Dr. Ching-Long Lin); 08/01/2013– 05/31/2018.

Selected Publications

  Methodology & Theory

  Application & Case Study